Pharmaceutical advertising joins the Super Bowl with Bristol Myers Squibb’s SOTYKTU in a soul-baring spot edited by BANDIT. The ad was created by Humancare.

SOTYKTU, the brand name for Deucravacitinib, treats moderate to severe plaque psoriasis in adults. In the spot, one woman finds confidence before a career-changing conference; meanwhile, her husband finds his own dose of free spirit on vacation, much to the chagrin of their preteen daughter.